Haemochromatosis, also spelled hemochromatosis, also called hereditary haemochromatosis, siderophilia and bronze diabetes, is a hereditary disease characterized by excessive absorption of dietary iron resulting in a pathological increase in total body iron stores. Humans, like virtually all animals, have no means to excrete excess iron. Excess iron accumulates in tissues and organs disrupting their normal function. The most susceptible organs include the liver, adrenal glands, the heart and the pancreas; patients can present with cirrhosis, adrenal insufficiency, heart failure or diabetes. The hereditary form of the disease is most common among those of Northern European ancestry, in particular those of British or Irish descent.
Haemochromatosis less often refers to the condition of iron overload as a consequence of multiple transfusions. More preferred terms in the United States include for transfusional iron overload or hemosiderosis used synonymously. Those with hereditary anemias such as beta-thalassemia major, sickle cell anemia, and Diamond-Blackfan anemia who require regular transfusions of red blood cells are all at risk for developing life-threatening iron overload. Older patients with various forms of bone marrow failure such as with myelodysplastic syndrome who become transfusion-dependent are also at risk for iron overload.
2 comments:
Foods containing calcium such as cottage cheese, yogurt, carrots, etc are great for slowing down iron absorbtion.
Drinks that have tannins work very well also. Black tea and my favorite, green tea are very helpful. Most herb teas do not contain tannins.
HH sufferrers should drink lots of water every day to keep the blood thin for easier phlebotomies and to keep the kidneys nice and flushed out. You can find lots of tips from Pat at his blog:
Http://ironoverload.info
In hemochromatosis, iron can build up in most of your body’ s organs, but especially in the liver, heart, and pancreas. When this happens, the iron can poison the organs and lead to organ failure.
If Hereditary Hemochromatosis is not treated liver disease may be fatal. Hemochromatosis can lead to enlargement, cirrhosis or cancer of the liver.
Heart Problems: Hemochromatosis can cause irregular heart rate or rhythm and lead to heart failure
Pancreas: Hemochromatosis can lead to diabetes mellitus.
The morbidity and mortality of Hereditary Hemochromatosis can be reduced by early diagnosis and treatment by phlebotomy or blood letting.
Bloodletting or deironing often results in considerable improvement in the health of patients who suffer from Hereditary Hemochromatosis.
Early diagnosis and treatment are important. Treatment may be able to prevent, delay, or sometimes reverse complications of the disease. More tips:
http://ironoverload.info
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